Estados psicopatológicos en pacientes con síndrome de fatiga crónica, asociada a sensibilidad química múltiple o no / Psychopathologic status in patients with chronic fatigue syndrome, associated or not with multiple chemical sensitivity

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Health-related quality of life in patients with chronic fatigue syndrome: group cognitive behavioural therapy and graded exercise versus usual treatment. A randomised controlled trial with 1 year of follow-up.

Chronic fatigue syndrome (CFS) produces physical and neurocognitive disability that significantly affects health-related quality of life (HRQL). Multidisciplinary treatment combining graded exercise therapy (GET) cognitive behavioural therapy (CBT) and pharmacological treatment has shown only short-term improvements. To compare the effects on HRQL of (1) multidisciplinary treatment combining CBT, GET, and pharmacological treatment, and (2) usual treatment (exercise counselling and pharmacological treatment) at 12 months of follow-up. Prospective, randomized controlled trial with a follow-up of 12 months after the end of treatment. Patients consecutively diagnosed with CFS (Fukuda criteria) were randomly assigned to intervention (n = 60) or usual treatment (n = 60) groups. HRQL was assessed at baseline and 12 months by the Medical Outcomes Study Short-Form questionnaire (SF-36). Secondary outcomes included functional capacity for activities of daily living measured by the Stanford Health Assessment Questionnaire (HAQ) and comorbidities. At baseline, the two groups were similar, except for lower SF-36 emotional role scores in the intervention group. At 12 months, the intervention did not improve HRQL scores, with worse SF-36 physical function and bodily pain scores in the intervention group. Multidisciplinary treatment was not superior to usual treatment at 12 months in terms of HRQL. The possible benefits of GET as part of multidisciplinary treatment for CFS should be assessed on an individual patient basis.

Relación entre el síndrome de fatiga crónica y el patrón de conducta tipo A / Relationship between chronic fatigue syndrome and type A behaviour

Fundamento y objetivo: Evidenciar la relación entre el patrón de conducta tipo A (PCTA) y el síndrome de fatiga crónica (SFC). Pacientes y método: Para evaluar el PCTA se ha administrado el inventario del JAS (Jenkins Activity Survey ‘cuestionario de actividad de Jenkins’) a 82 pacientes diagnosticados de SFC según los criterios de Fukuda (Centro para el Control y prevención de enfermedades, 1994). Se han comparado las medias de las puntuaciones típicas obtenidas en el JAS de los pacientes con SFC con las medias de las puntuaciones obtenidas en la población general (controles sanos) y en los pacientes con cardiopatía isquémica (controles patológicos). Resultados: Los pacientes con SFC tienen una media de las puntuaciones típicas de 5 puntos por encima de la media de la población general y de 2 puntos por encima de los enfermos de cardiopatía isquémica. Conclusiones: El PCTA es un factor que está relacionado con el SFC. Una alta puntuación en el JAS debería tenerse en cuenta en el abordaje terapéutico de estos enfermos (AU)

Background and objective: To quantify the relationship between Chronic Fatigue Syndrome (CFS) and Type A Behaviour Pattern (TABP) Patients and method: The Jenkins Activity Survey (JAS) was administered to 82 patients diagnosed with CFS to determine the prevalence of TABP. Subjects’ mean z scores on the JAS were compared with those from the general population (healthy controls) and from patients with ischemic cardiopathy (pathologic controls). Results: CFS patients’ mean score on the JAS was 5 points higher than that of the general population (healthy controls) and 2 points higher than that of patients with ischemic cardiopathy. Conclusions: TABP appears to be related with CFS and should be taken into account in the treatment of these patients (AU)

[Relationship between chronic fatigue syndrome and type A behaviour]. / Relación entre el síndrome de fatiga crónica y el patrón de conducta tipo A.

BACKGROUND AND OBJECTIVE: To quantify the relationship between Chronic Fatigue Syndrome (CFS) and Type A Behaviour Pattern (TABP) PATIENTS AND METHOD: The Jenkins Activity Survey (JAS) was administered to 82 patients diagnosed with CFS to determine the prevalence of TABP. Subjects' mean z scores on the JAS were compared with those from the general population (healthy controls) and from patients with ischemic cardiopathy (pathologic controls). RESULTS: CFS patients' mean score on the JAS was 5 points higher than that of the general population (healthy controls) and 2 points higher than that of patients with ischemic cardiopathy. CONCLUSIONS: TABP appears to be related with CFS and should be taken into account in the treatment of these patients.

Aumento significativo del estado funcional y descenso del grado de fatiga en los pacientes con síndrome de fatiga crónica tras la realización de psicoterapia cognitivo-conductual en grupo / Significant increase of functional status and decrease of fatigue in patients with chronic fatigue syndrome after completing cognitive behavioural group therapy

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